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But the infection may linger longer if your immune system is very weak It treats cold sores around the mouth (caused by herpes simplex ), shingles (caused by herpes zoster ), and chickenpox. Sitavig will not treat genital herpes. Aciclovir can be used: • To treat herpes and other viral infections caused by the herpes virus (varicella zoster) such as chicken pox and shingles • To prevent recurrent attacks of herpes simplex • To help prevent those who have low immune systems from getting herpes infections. In vitro, acyclovir triphosphate stops replication of herpes viral DNA. BEFORE YOU TAKE ACICLOVIR TABLETS. Since July 2020, our clinic has used acyclovir as a primary antiviral for COVID-19 treatment. Sitavig is for use in treating only cold sores on the lips. 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It works by killing or stopping the growth of viruses. It may be used to treat herpes infections such as: Chickenpox Cold sores Genital herpes Shingles. These include herpes zoster ( shingles ), genital herpes, and varicella ( chickenpox). Acyclovir slows the growth and spread of the herpes virus in the body. It is also used to prevent having regular outbreaks of genital herpes. Acyclovir is best used as soon as possible after the symptoms of herpes infection or shingles (for example, pain, burning, blisters) begin to appear. This medicationis also used to treat outbreaks of genital herpes. This drug doesn’t cure herpes infections. Acyclovir is a nucleoside analogue used to treat herpes virus infections, which is selective to the herpes simplex enzyme thymidine kinase. 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