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Storage And Handling SITAVIG buccal tablets are supplied as off-white tablets containing 50 mg of acyclovir Sitavig® (acyclovir) 50 mg buccal tablet is indicated for the treatment of recurrent herpes labialis (cold sores) in immunocompetent adults. This medication will not treat colds, the flu, or infections caused by bacteria Acyclovir Lauriad (®) is a new topical agent that was approved by the US FDA in 2013 for the treatment of recurrent herpes labialis, which affects approximately 20-40% of the population worldwide. It also comes in a cream and ointment you apply to your skin. Dosage Form; Route: Buccal tablet; oral. The drug is a muco-adhesive tablet, applied to the upper gum at the onset of prodromal symptoms Acyclovir is also available as a capsule, suspension, and buccal tablet that you take by mouth. The delayed-release buccal tablet is usually applied with a dry-finger within 1 hour after cold sore symptoms (itching, redness, burning or tingling) begin, but before the cold sore appears. Use this medicine (acyclovir buccal tablets) as ordered by your doctor. SITAVIG tablets are round, off-white tablets, with a rounded side and a flat side. This medication does not kill the virus and it may still be possible to spread the virus to others. Follow all instructions closely. SITAVIG is a buccal tablet containing 50 mg of acyclovir. The tablets are marked with an “AL21” on the flat side. It is usually taken as a single (one-time) dose Acyclovir buccal tablet is used to treat the symptoms of herpes simplex virus infection on the lips and around the mouth (cold sores) in adults with normal immune systems. Recommended Studies: Two options: in vitro study, or in vivo and in vitro study. Read all information given to you. In vitro option: Bioequivalence based on in vitro studies if the test formulation is qualitatively and quantitatively the same (Q1/Q2) as the reference listed drug (RLD). Use within 1 hour after the first signs of a cold sore. Although acyclovir will not cure herpes simplex, it may help the sores to heal faster and relieve some of the pain and discomfort ACYCLOVIR (ay SYE kloe veer) helps manage infections, such as cold sores, caused by viruses. IMPORTANT SAFETY INFORMATION Sitavig® (acyclovir) 50 mg buccal tablet should not be used in patients with known hypersensitivity to acyclovir, milk protein concentrate, or any other component of the product..